The exact way that topical diclofenac helps this condition is unknown. Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [25] Professor Peter Weissberg, Medical Director of the British Heart Foundation said, "However, the increased risk is small, and many patients with chronic debilitating pain may well feel that this small risk is worth taking to relieve their symptoms". [60][61], "Diclo" redirects here. PCD Pharma Franchise, Third Party Manufacturing, diethylamine B.P 1.16 % w/w linseed oil B.P. [50] It is more expensive than diclofenac, but the cost is dropping[when?] Diclofenac topical patch and topical system is used to treat acute pain caused by minor strains, sprains, and contusions (bruises). Studies in Pakistan showed diclofenac caused acute kidney failure in vultures when they ate the carcasses of animals that had recently been treated with it. [3], The name "diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. However, this medicine does not cure osteoarthritis and will help you only as long as you continue to use it. [citation needed]. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Get contact details and … [medical citation needed], The action of one single dose is much longer (6 to 8 hr) than the very short 1.2–2 hr half-life of the drug would indicate. [56], "The loss of tens of millions of vultures over the last decade has had major ecological consequences across the Indian Subcontinent that pose a potential threat to human health. In many places, populations of feral dogs (Canis familiaris) have increased sharply from the disappearance of Gyps vultures as the main scavenger of wild and domestic ungulate carcasses. At a meeting of the National Wildlife Board in March 2005, the Government of India announced it intended to phase out the veterinary use of diclofenac. These vendors are known for their consistently superior quality enabling us to sustain our reputation in the industry. Physicians should measure transaminases periodically in patients receiving long-term therapy with diclofenac. Drug-sensitive species and individual humans are initially assumed to lack genes expressing specific drug detoxification enzymes. In 2016 Voltarol was one of the biggest selling branded over-the-counter medications sold in Great Britain, with sales of £39.3 million. Catering to the varied needs of a large section of the customers in the industry we offer a wide range of products including Pain Relief Spray, Burn Relief Spray, Povidone Iodine Spray, Nasal Spray, Pepper Spray, Wound Spray, Stretch Mark Removal Spray, Anti Fungal Spray, Throat Infection Relief Spray, Topical Spray, Hair Regrowth Spray, Mouthwash Spray, First Aid Spray Kit, Dandruff and Fungal Infection Relief Spray and Acne Relief Spray. It was approved as a prescription drug and was indicated for the relief of the pain of osteoarthritis of joints responsive to topical treatment; in particular, it was prescribed for the joints in the hands, knees and feet. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). [36], Diclofenac may also be a unique member of the NSAIDs. Further our product quality is sustained by the skilled experts engaged in the production of these products. We use only the best grade of industry approved materials in the formulation of these products. [28] A very large study of 1,028,437 Danish users of various NSAIDs or coxibs found the "Use of the nonselective NSAID diclofenac and the selective cyclooxygenase-2 inhibitor rofecoxib was associated with an increased risk of cardiovascular death (odds ratio, 1.91; 95% confidence interval, 1.62 to 2.42; and odds ratio, 1.66; 95% confidence interval, 1.06 to 2.59, respectively), with a dose-dependent increase in risk. They start breeding only at the age of six and only 50% of young survive. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Important is that diclofenac inhibits COX-1 and COX-2 with relative equipotency. This product is available in the following dosage forms: Portions of this document last updated: Nov. 01, 2020.

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